But now, this exclusive club has a new member — two groups report the detailed biochemistry and structure of the Mycobacterium tuberculosis (Mtb) 20S proteasome. In a parallel collaborative ...

While NQO1, a 20S proteasome gatekeeper, protects a subset of IDPs from degradation, another more general mechanism of IDP stabilization that we propose is the 'nanny' model mechanism. Second ...