This is the first published study of the effects of a 5-HT 1a partial agonist on acute thermal sensation and pain perception in human subjects. Morphine induced a significant increase in the heat ...

The authors suggest that other genetic factors also determine the time until ejaculation, and are continuing to investigate the role of 5-HT receptors and metabolic pathways in the regulation of ...

HC Wainwright began coverage on shares of Bright Minds Biosciences (NASDAQ:DRUG – Free Report) in a report released on Friday, Marketbeat Ratings reports. The firm issued a buy rating and a $85.00 ...

Analysts at Cantor Fitzgerald initiated coverage on shares of Bright Minds Biosciences (NASDAQ:DRUG – Get Free Report) in a note issued to investors on Friday, MarketBeat.com reports. The brokerage ...

The article has been submitted for peer review in a major journal. ABSTRACT: PRX-3140 is a partial agonist to the 5-hydroxytryptamine receptor 4 (5-HT4) and a ligand for the sigma-1 (S1R ...

The authors then tested prolonged administration of 5-HT 1-receptor agonists in 140 rats with 6-hydroxydopamine-induced lesions that were receiving daily L-DOPA. Coadministration of the 5-HT 1 ...

Sumatriptan (as succinate) 3mg/0.5mL; soln for SC inj. Sumatriptan binds with high affinity to human cloned 5-HT 1B/1D receptors. Sumatriptan presumably exerts its therapeutic effects in the ...

Background: Buspirone is a partial 5-HT 1A receptor agonist. Animal studies have shown that modulation of serotoninergic transmission at the 5-HT 1A receptor can induce analgesia in acute pain models.