Evidence supports the idea that antineoplastic drugs and irradiation can initiate ... and the pharmacologic properties of 5-HT 3-receptor antagonists, the oral use of these agents is rational.

It is very difficult to determine the duration of action of 5-HT 3-receptor antagonists at vagal afferent neuronal receptors. A surrogate test that may have clinical relevance is the duration of ...

leading to the more frequent and sometimes unbridled use of these drugs in the medical community. We herein describe the likely mechanisms of action of aldosterone-receptor antagonists ...

“In addition, since these drugs act by different mechanisms, it is likely that telcagepant and other CGRP receptor antagonists will help some patients who are not helped by triptans,” says Russ ...