and other tissue types (Fig. 2). The company is proceeding with additional capsid campaigns derived from AAV9, AAV5, and other AAV serotypes to identify novel capsids optimized for AAV delivery ...

However, the tropism (selective tissue targeting) of AAVs isolated from nature is one shortcoming, Bu notes. “The tropism of natural AAV serotypes is limited,” he says. “They also tend to ...

2 However, not all vectors have equivalent properties, with some possessing higher packaging capacities, delivery efficiencies, tissue specificities, and immunogenicity. 4 For instance, different AAV ...

The final, formatted version of the article will be published soon. Olfactory sensory neurons within the nasal epithelium detect volatile odorants and relay odor information to the central nervous ...

AMSBIO have packaged these indicators into the most commonly used AAV serotypes (AAV8 and AAV9). AMSBIO also has the experience and expertise ... or other physiological intracellular processes such as ...

New Vericheck ddPCR Empty-Full Capsid Kits for AAV Serotypes 2 and 8 Provide Precise Measurement of Viral Titer and Capsid ...

This approach, thanks to its easy applicability to multiple AAV serotypes, reduced processing steps, and comparable genome recovery rates, seems well-positioned to edge out immunoaffinity ...

This study aimed to characterise the natural history of AAV infection in the liver and its consequence in tumour development. Design Viral DNA was quantified in tumour and non-tumour liver tissues of ...