found that it is caused by mutations in the gene that codes for ALK2/ACVR1, a receptor involved in regulating bone development. Approximately 97% of people with FOP have the same mutation 5.

Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disorder in which abnormal bone formation progressively replaces muscle and connective tissues due to a mutation in the ACVR1 gene ...

found that it is caused by mutations in the gene that codes for ALK2/ACVR1, a receptor involved in regulating bone development. Approximately 97% of people with FOP have the same mutation.