Twenty-one patients died of carcinoma in various tissues other than the pancreas ... the pancreas showed squamous metaplasia of the duct epithelium, with acinar dilatation and areas of fat ...

TLS are accumulations of lymphoid cells that share similar cellular ... The organoids expressed epithelial ductal and acinar markers and recapitulated the epithelial diversity.

B1 shows exocrine pancreatic tissue fibrosis ... (E) Representative acinar atrophy and decreased zymogen granules indicated by arrowheads. (F) Epithelium mucus secretory cell metaplasia indicted ...