In nine of 11 adult patients treated with actinomycin D a characteristic skin eruption developed, with predictable progression from erythema to papules and pustules and from face to trunk.

infusion over 30 min Actinomycin D 0.5 mg iv. bolus Folinic acid rescue ... actinomycin (EMA)/cyclophosphamide and vincristine (CO) combination chemotherapy if the hCG is more than 100–300 ...

Subsequently, she received chemotherapy with vincristine, actinomycin D and ifosfamide, and was followed up with serial imaging. At 18 months, MRI showed no evidence of residual tumor, and ...