Therefore, tempering drug-induced amplification of dopamine signaling is one approach to reduce the powerful effects of drugs on the brain. We have been exploring the potential of the neuromodulator, ...

During the day, our brains accumulate something called "sleep pressure" – your body’s way of signalling that it needs rest, driven in part by a chemical called adenosine. Adeel explains that ...

Caffeine, or to use its systematic name, 1,3,7-trimethylxanthine, is produced by more than 60 plant species, from coffee and ...

Endogenous adenosine, a bioenergetic molecule, has potent neuroprotective and neuromodulatory actions and regulates the release of various neurotransmitters involved in the phenomena of drug ...

Numerous agonists and antagonists of adenosine receptors or drugs modifying the release of adenosine itself are under development for potential therapeutic applications. Thus, due to its varied ...

The pharmacological effects of beta 2-adrenoceptor agonist drugs are at least in part attributable ... the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3, 5 ...