The cases included 25 diffuse low-grade astrocytomas (grade II), 20 anaplastic astrocytomas (grade III) and 60 glioblastomas (grade IV) according to WHO criteria. [2] The characteristics of the ...

Against this background, Wick et al. 4 conducted the NOA-04 trial of radiotherapy versus chemotherapy in 318 patients with newly diagnosed anaplastic glioma who were randomized to receive either ...