Angiogenic sprouting is controlled by a balance of activators and inhibitors. Angiogenesis inhibitors suppressing the proliferation or migration of endothelial cells include angiostatin (an ...

For example, whereas other inhibitors could block leptin-induced angiogenesis in adipose tissue, leptin could still control food intake and obesity through the central nervous system (except in ...

After decades of work, Dr. Folkman and his team are now watching as clinical trials begin with two recently discovered angiogenesis inhibitors, endostatin and angiostatin. In this interview ...

"Then we got excited." Further tests showed that NK-B could inhibit angiogenesis in four ways. It prevents the production of vascular endothelial growth factor (VEGF), a key stimulator of blood ...

The process is regulated by a balance of endogenous angiogenesis stimulators (such as vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) and the angiopoeitin family), ...