Bacterial pathogens use many strategies to avoid being detected by the host's immune system. New work published in Nature indicates that Bacillus anthracis, the causative agent of anthrax, targets ...

Anthrax LF is internalized via a dynamin dependent pathway and 34 delivered to early endosomes. There the toxin receptor complex is sorted into nascent ILVs. Anthrax PA forms a channel into the ...

The structures of all three proteins that comprise the anthrax toxin, and now small-molecule inhibitors of the toxin, have been reported 4. Structural studies are now central to devising and ...

A need exists for alternate or supplemental treatment modalities, particularly those that neutralize anthrax toxins. The focus has been on passive immunization with monoclonal and polyclonal ...

Between 1993 and 1995, Aum Shinrikyo tried as many as 10 times to spray botulinum toxin and anthrax in downtown Tokyo. Just why the attacks failed is unclear, but some experts suspect the cult did ...

where they requested that the United States set up production facilities sufficient to produce large amounts of anthrax bacterial spores (called "Agent N") and botulinum toxin ("Agent X").