Tumor-associated carbohydrate (TAC) antigens are prime candidates for cancer vaccines because of their involvement in metastasis and the rapid growth of tumors. But their inability to elicit a T ...

According to Altindis, molecular mimicry is one autoimmune mechanism in which the immune system cannot distinguish between a foreign antigen that shares a structural similarity with a host protein and ...

This gives us a good starting point for understanding the molecular basis of peptide mimicry. Moreover, to understand how peptides may rationally be used as immunogens, we are investigating select ...