Apoptosis can be triggered by the immune system or by the interaction of viral proteins with host signalling pathways. Inhibition of apoptosis has mixed effects on viral titre but typically has a ...

DEATH DUEL: One TNF receptor 1 pathway activates apoptosis, another triggers gene expression-roles in seeming opposition, says David Goeddel. H. Hsu, H Shu, M. Pan, D.V. Goeddel, "TRADD-TRAF2 and ...

Altogether, these examples demonstrate how autophagy can prevent apoptosis and show the metabolic pathways through which cytoprotective autophagy can be stimulated. Autophagy-mediated cellular ...

Nanjing Reju Therapeutics Inc. has described tumor necrosis factor receptor type 1-associated DEATH domain protein (TRADD) inhibitors reported to be useful for the treatment of inflammatory-related ...