This important study by Bi and colleagues employed a clever genetics screen to uncover the role of the GidB rRNA methylase in translation fidelity, under certain conditions, in Mycobacterium smegmatis ...

The rRNA of the small subunit, particularly the 16S rRNA in prokaryotes and the 18S rRNA in eukaryotes ... inhibit bacterial protein synthesis by binding to and disrupting the function of bacterial ...

Caption Streptothricin-F (yellow spheres) bound to the 16S rRNA (green) of the bacterial ribosome impinges on the decoding site where tRNA (purple) binds to the codon of the mRNA (blue). This ...

Bacteria modify their ribosomes when exposed to widely used antibiotics, according to research published in Nature Communications. The subtle changes might be enough to alter the binding site of ...