During development, a single (basal) layer of primitive epithelium initially ... Figure 2: Potential mechanisms for p63 maintaining stem-cell populations.

Renewal of the epidermis relies on stem cells located in its lowest layer ... available for the keratinocytes is lower in the basal layers of the epidermis compared to the top layers that are ...

These cell culture systems are made of a single layer of stem cells, which researchers grow on scaffolds ... Monolayer systems cultured on porous membranes replicate both the luminal and basal sides ...