After treating a tumour with chemotherapy and radiotherapy, cells known as senescent cells can appear. These are cells that do not divide, are involved in the ageing process and are resistant to cell ...

BAD then bound to 14-3-3 instead of Bcl-2 or Bcl-X L, resulting in the liberation of the anti-apoptotic proteins and the consequent promotion of cell survival. BAD protein in which one or both of ...

After treating a tumor with chemotherapy and radiotherapy, cells known as senescent cells can appear. These are cells that do ...

BCL-2 antagonists will probably begin their commercial lives as products that disable the anti-apoptotic machinery and restore chemosensitivity, pairing favourably with conventional cytotoxic ...

A new study describes a molecular mechanism that could drive the design of strategies to eliminate senescent cells in cancer ...