尤其是MCL-1。 就像刘备,关羽,张飞一样,BCL-2,MCL-1和BCL-XL是三个好基友,功能差不多,都是阻止细胞自杀。只要有其中一个,细胞就不容易死。
BCL-2 inhibitors, such as venetoclax (Venclexta) work by targeting the BCL-2 protein, which plays a key role in preventing apoptosis, or programmed cell death. According to John Seymour, MD, ...