Therefore, we studied MEAC formation and the effects of MEAC binding on CLL cells. In cell line studies, both intrinsic (spontaneous or camptothecin-induced) and extrinsic (FasL- or anti-Fas ...

CLL and ALL begin in the bone marrow, where blood cells are usually made. Specifically, it starts in a type of bone marrow cell called lymphocytes. (That’s what the first “L” in CLL and ALL ...

Progress in this regard has been hampered by the lack of CLL cell lines that accurately represent the morphology and biological characteristics of this tumor. The NF-κB family of transcription ...

Treatment for CLL continues to change. Doctors are using newer targeted cancer drugs ... After you have your chemotherapy and other treatments you have your donor’s stem cells. You have these through ...

But the bottom line is a patient can enjoy a very ... American Cancer Society: “Signs and Symptoms of Chronic Lymphocytic Leukemia,” “Stem Cell Transplant for Chronic Lymphocytic Leukemia ...

Developments in chronic lymphocytic leukemia (CLL) this year included the first CAR T-cell therapy approval for ... and obinutuzumab triplet a potential first-line standard treatment for patients ...

AbbVie and Roche’s Venclexta is making headway as a second-line chronic lymphocytic leukaemia (CLL) treatment, and a new US filing could extend its use into the first-line setting. Roche has ...

Ibrutinib normalizes RBC aggregation in CLL, potentially reducing thrombotic risks by mitigating blood flow complications. Obinutuzumab/venetoclax combination does ...

A high tumor burden with large numbers of B cells results in more rapid elimination. Single agent: 55% overall response rate in untreated chronic lymphocytic leukemia (CLL). Fludarabine plus ...

Brian Koffman, executive VP and CMO of CLL Society in the press ... also approved in the US as a second-line treatment for relapsed or refractory large B-cell lymphoma (LBCL) and outside the ...

During a Case-Based Roundtable® event, Nakhle Saba, MD, and participants discussed the data supporting the 2 newer BTK ...