Gene-editing tools such as CRISPR/Cas9 can be used to create isogenic cell lines, which can be further used to model a specific patient population. An isogenic cell line was created to model ...

2024年12月16日，生命科学学院刘亮教授团队在《Nucleic Acids Research》期刊上在线发表了题为“DNA target binding-induced pre-crRNA processing in type II and V CRISPR-Cas systems”的研究论文，首次揭示了靶标核酸的结合能够激活CRISPR-Cas系统效应蛋白对pre-crRNA的反式切割活性 ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

CRISPR is a technology that can be used to edit genes and, as such, will likely change the world. The essence of CRISPR is simple: it’s a way of finding a specific bit of DNA inside a cell.

For modern biotherapeutics, cell line development workflows must include more than just automated liquid handling.

Biotechnology is revolutionizing our understanding of wildlife, allowing scientists to unlock secrets previously hidden in ...

To streamline and accelerate tool development, TMO has also integrated Gibson Assembly into its CRISPR workflows, making it easier to clone large DNA fragments efficiently. On December 20 ...

51% of the business is held by the top 14 shareholders Ownership research along with analyst forecasts data help provide a good understanding of opportunities in a stock Every investor in CRISPR ...