为了更准确地表明小胶质细胞在突触发育中的作用，来自爱丁堡大学的研究团队构建了小胶质细胞缺失的转基因小鼠（Csf1r ∆FIRE/∆FIRE ），探索了在 ...

吡昔替尼是一种小分子酪氨酸激酶抑制剂，能够抑制集落刺激因子 1 受体 （CSF1R），CSF1R 配体的过表达促进滑膜中细胞的增殖和积累。此外 ...

Circulating tumor DNA for predicting complete response to total neoadjuvant therapy in locally advanced rectal cancer: ENSEMBLE-2. This is an ASCO Meeting Abstract from the 2025 ASCO Gastrointestinal ...

By Dr. Priyom Bose, Ph.D. Research shows male microglia are more sensitive to disrupted CSF1R signaling, uncovering potential links to sex-based disparities in neurological disorders. Study: The ...