The gene encodes an enzyme in the liver called CYP2D6. Subsequently, they tested different drug compounds on engineered cell models to determine how the effect of the compound was influenced by ...

A drug–gene interaction occurs when a patient's genetic CYP450 type (e.g., CYP2D6 poor metabolizer) affects that patient's ability to clear a drug. A drug–drug–gene interaction occurs when ...

The gene encodes an enzyme in the liver called CYP2D6. Subsequently, they tested different drug compounds on engineered cell models to determine how the effect of the compound was influenced by ...