For solid tumors and hematological malignancies, CAR-NK cell treatment is a novel kind of cancer immunotherapy. CAR-NK cells work by killing cancer cells in a CAR-dependent way. CAR-NK cells and ...

Unlike CAR-T cells, NK cells don’t need genetic modification to recognize a specific threat — they act broadly without ...

本文研究结果表明，缺失NKG2A的CAR-NK细胞或有望能绕过患者 ... primary CD33-directed chimeric antigen receptor natural killer cells”的研究报告中，来自法兰克福 ...

If additionally enhanced with a chimeric antigen receptor, they are capable of fighting cancer cells in two ways. Another advantage of CAR-NK cells is that they have hardly caused any side effects ...

For the new therapy, these cells are derived from stem cells that originated from healthy adult donor tissue - called induced pluripotent stem cells (iPSCs) - to make therapeutic CAR-NK cells ...

So instead, Rezvani decided to add the CAR gene to natural killer (NK) cells. “These cells are part of the innate immune system, and they’re very good at recognizing and killing cancer cells ...

The Cambridge, Massachusetts-based biotech is the latest player in the emerging field of chimeric antigen receptor (CAR) NK cell therapies, which unlike the current generation of CAR-T therapies ...

A new area of cancer immunotherapy is enhancing therapeutic mAb-mediated CD16 activation of NK cells. CAR-NK cells containing multi-specific molecules made up of relatively stable CD16 and other ...

Glycostem is amongst the few NK cell producers to develop naked NK cell therapies before CAR (chimeric antigen receptor)-NK products (Fig. 1). “While there is clearly a place for both therapies ...

Opens in a new tab or window An investigational induced pluripotent stem cell-derived CAR natural killer cell therapy was well tolerated both as monotherapy and in combination with rituximab among ...

The first patient with relapsed/refractory acute myeloid leukemia has received KJ-C2320, an allogeneic CAR T-cell therapy ...

Unmodified natural killer (NK) cells work differently from the T-cells upon which CAR-T therapies are based – NKs are usually involved in killing cells that are infected with viruses, whereas T ...