Conclusion. Doripenem is an injectable carbapenem antibiotic with a spectrum of activity comparable to that of imipenem and meropenem. Its safety is similar to that of other carbapenems.
especially if the infections are difficult to treat because they are resistant to commonly used drugs. For example, Carbapenem-resistant Enterobacterales (CRE) are known to particularly affect ...
Traditionally, these infections can be effectively treated by the carbapenem class of drugs. In 2005, our institution initiated a protocol for use of ertapenem, a carbapenem, as the first-line ...
Drugs called carbapenems are used when an infection ... then this will continue to rise." Deaths from carbapenem-resistant K. pneumoniae have gone up from 341 in Europe in 2007 to 2,094 by 2015.
According to Chen’s study, even colistin, the last-resort drug for carbapenem-resistant infections, used alone or in combination with other drugs, is ineffective in fighting ST11 CR-HvKP.