As a part of the Regenerative Pharmacology Unit of the Drug Research Program, our group aims at discovering new ways to treat heart diseases by investigating the molecular mechanisms of cardiac ...

In hearts damaged by heart failure, the regeneration rate of cardiomyocytes was found to be 18–50 times lower than in a typical healthy heart. However, the researchers found that when a LVAD was ...

Myeong-Hwa Song. The team has unveiled an innovative technique to convert fibroblasts - common connective tissue cells - into mature and functional induced cardiomyocytes (iCMs). Their method ...

This diagram illustrates how the combination of fibroblast growth factor 4 and ascorbic acid activates the JAK2–STAT3 signaling pathway, promoting the maturation of induced cardiomyocytes (iCMs).

A research team led by Professor Yuma Yamada of Hokkaido University's Faculty of Pharmaceutical Science has developed a technique to promote cardiac regeneration by delivering mitochondrial ...

The award runs through the end of 2024 to support Sun’s research on, “Cardiomyocyte-specific Modified mRNA for Myocardial Regeneration in a Porcine Myocardial Infarction ... “This gene will turn on ...