Berry, R. Effects of interactions of cell cycle-specific cytotoxic drugs and X-radiation on survival of cell reproductive capacity. Br J Cancer 32, 752 (1975). https ...
Several tumour-suppressor proteins monitor intrinsic and extrinsic signals and integrate these inputs to decide whether the cell should remain in a quiescent state or enter into the cycle of ...
Chemotherapy targets cancer cells by disrupting DNA replication and mitotic processes, despite side effects on healthy cells.
Since 2000, antibody-drug conjugates have been approved by the Food and Drug Administration for various cancer types, such as ...
By inferring proliferation rates from single-cell genomics, SPRINTER enhances understanding of tumor evolution and identifies ...
We have recently generated cell lines with resistance to both in-house and external CHK1 ... the evidence that inhibition of CHK2 will also sensitise p53 deficient tumour cells to genotoxic cancer ...
Cytokinesis is a key event in the cell cycle requiring tight coordination of mitotic spindle assembly, actomyosin contractility and membrane dynamics, but the mechanisms that regulate cytokinesis are ...
Molecular Cellular Pharmacology Graduate Program, University of Wisconsin-Madison, Madison, USA Department of General Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan ...