Berry, R. Effects of interactions of cell cycle-specific cytotoxic drugs and X-radiation on survival of cell reproductive capacity. Br J Cancer 32, 752 (1975). https ...
The breast cancer drug Herceptin, for example ... division rates or inhibiting normal controls on the system, such as cell cycle arrest or programmed cell death. As a mass of cancerous cells ...
Cytokinesis is a key event in the cell cycle requiring tight coordination of mitotic spindle assembly, actomyosin contractility and membrane dynamics, but the mechanisms that regulate cytokinesis are ...
We have recently generated cell lines with resistance to both in-house and external CHK1 ... the evidence that inhibition of CHK2 will also sensitise p53 deficient tumour cells to genotoxic cancer ...
Molecular Cellular Pharmacology Graduate Program, University of Wisconsin-Madison, Madison, USA Department of General Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan ...