Berry, R. Effects of interactions of cell cycle-specific cytotoxic drugs and X-radiation on survival of cell reproductive capacity. Br J Cancer 32, 752 (1975). https ...
Repurposing old drugs for new treatments is not a new ... resistance revealed by integrated multi-omics of evolved cancer cells, Cell Cycle (2024). DOI: 10.1080/15384101.2024.2402191 ...
We have recently generated cell lines with resistance to both in-house and external CHK1 ... the evidence that inhibition of CHK2 will also sensitise p53 deficient tumour cells to genotoxic cancer ...
Since 2000, antibody-drug conjugates have been approved by the Food and Drug Administration for various cancer types, such as ...
Chemotherapy targets cancer cells by disrupting DNA replication and mitotic processes, despite side effects on healthy cells.
By inferring proliferation rates from single-cell genomics, SPRINTER enhances understanding of tumor evolution and identifies ...
This is frequently diagnosed in dogs that were never spayed and the only type of cancer in dogs that has research showing ...
Cytokinesis is a key event in the cell cycle requiring tight coordination of mitotic spindle assembly, actomyosin contractility and membrane dynamics, but the mechanisms that regulate cytokinesis are ...
New research into a chemical produced by a caterpillar fungus that has shown promise as a possible cancer ... cell growth signals. The discovery is an important step towards developing new drugs ...
The PDA-ICG nanoprobe offers a novel approach for visualizing senescent cells, crucial for understanding their role in tumor ...