an expert in the field of cell-cycle regulation and one of the authors of this study, hypothesized that Cdt1 and Geminin would be good candidates for making fusion protein sensors that would ...

Cell-cycle regulation of canonical histone mRNA. Figure 5: Two models for histone variant function in core histone mRNA 3′ end formation. During this time the demand for histone proteins in many ...

MicroRNAs are short RNA molecules that do not encode for proteins but rather regulate ... implicated in a broad range of stem cell roles in both healthy and diseased tissues. MicroRNAs show great ...

and currently many small-molecule anti-cancer drugs are targeting molecules involved in cell cycle regulation. Cell division is composed of a complex network of interactions between proteins, ...

Protein modifications are key to cell survival because they ensure they do what they are supposed to do in a healthy system.

is a ubiquitin- and RNA-binding protein, highly conserved in metazoans. Despite its abundance, its functions have only recently started to be characterized. Several studies have demonstrated the ...

The stress of heat and oxidative damage during exercise causes disruption to intestinal epithelial cell tight junction proteins resulting in increased permeability to luminal ... The purpose of this ...

When gene regulation fails ... in the regulatory processes that govern cell identity. Researchers discovered that a chemical alteration on a single protein, histone H3, is essential for ...

Researchers have discovered a mechanism steering the evolution of multicellular life. They identify how altered protein folding drives multicellular evolution.

Iron is an essential element, with iron-containing proteins exerting a variety of vital functions ... activation of signalling pathways, cell cycle regulation, differentiation and cell death. Such ...