A thermal stability-based proteomic analysis identifies cytoplasmic PEBP1 as a mediator of mitochondrial dysfunction-induced stress response, highlighting its potential role in cellular adaptation ...

Blocking this stress response or the lipid synthesis pathway reversed symptoms of Alzheimer's disease in preclinical models. "These findings reveal a critical link between cellular stress and the ...

Therefore the stem-like cells are likely to exhibit a distinct gene expression program that is compatible with stem-like properties such as unlimited replicative potential and improved control of ...

According to research, PSAT1, PSRC1, COLEC12, HP, and PLLP may play a role in small cell lung cancer metabolism, immune ...

Most people associate sunburns with DNA damage -- it's what we've been taught in textbooks and by dermatologists for years.

Deep within the nucleus of every cell lies a structure smaller than a pinpoint that may hold the secret to aging. Scientists ...

My group focuses on understanding cell signaling pathways primarily linked with the ubiquitin and autophagy systems and frequently altered in diseases, including neurodegenerative disease. To this end ...

Various immune pathways in the host ... and extracellular microorganisms utilize programmed cell death mechanisms to initiate ...

Nicotinamide adenine dinucleotide (NAD+) is an essential coenzyme ubiquitously present in all living cells, playing a pivotal ...