1983). After determining that the HD gene is located on chromosome 4, the members of the Huntington's Disease Collaborative Research Group (HDCRG) joined forces and spent the next 10 years working ...

Huntington's disease (HD) is a hereditary neurodegenerative disorder caused by a mutation in the gene called huntingtin on chromosome 4. HD is inherited in an autosomal dominant fashion, so that each ...

Researchers have made a major breakthrough in our understanding of Huntington's disease. This genetic disorder has long been known to be caused by mutations in the huntingtin gene, which leads to the ...

Huntington's disease is a neurodegenerative disorder that is usually fatal about 15 to 20 years after a patient is diagnosed. It is known ... | Genetics And Genomics ...

Scientists have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads ... of Biomedical Science and Genetics at Harvard Medical ...

A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in ...

This type of "somatic expansion" occurs in only the specific types of brain cells that later die in Huntington's disease ... of Biomedical Science and Genetics at Harvard Medical School, and ...

Less than a month after researchers unveiled that a “ticking DNA clock” is behind Huntington’s disease (HD), scientists have now identified an antisense oligonucleotide (ASO) that can slow ...

The field of Huntington’s disease research has been undergoing a radical reshaping of how the brain-ravaging disease — and what drives it — is understood. After decades focused on the notion ...

Huntington’s disease is an incurable neurodegenerative disease that affects muscle coordination and cognitive function. Symptoms of the disease usually start to develop around middle age.