Deciphering the structures of proteins is critical to structural drug design. Cryo-electron microscopy (cryo-EM) now offers a radically different way to study the structure of large biomolecules ...

The images produced with a cryo-electron microscope can only be as good as the sample that goes into it. That's why Jiro Usukura, at the Structural Biology Research Center, Nagoya University ...

For his final year project, Matthew had the chance to use Sheffield’s brand new cryo-electron microscope (worth around £2.5 million) as he studied amyloidβ, the causative agent of Alzheimer’s disease.

• Cryo-Autoloader for automated and contamination-free loading of cassettes, containing up to 12 Autogrids • Three-condenser lens system for automated, continuous parallel sample illumination tested ...

The importance of this technology has also been recognized in Thailand, and the first cryo-electron microscope was introduced at Mahidol University last year. In this research, we aim to provide ...

Cryo electron microscopy (cryo EM) has revolutionized our understanding of the intricate molecular machinery that governs life. In this article, we discuss what cryo EM is, how it works, it's ...

The GW4 Facility for High-Resolution Electron Cryo-Microscopy provides access to cryo-microscopy to researchers in south west UK and beyond. In 2017, the GW4 Alliance opened a £2.3 million shared ...

My main research interests are functional and structural analyses by 3-D cryo-electron microscopy of cytoskeletal assemblies and large macromolecular structures as well as cellular organelles. We ...

It enables ambient temperature and cryo-electron microscopy of single particle or tomography samples to obtain preliminary data prior to more detailed analysis on higher specification TEMs. FEI Tecnai ...

Our expertise in EM sample preparation and imaging allows us to support biomedical and translational research. With our cryogenic electron microscopy, or cryo-EM, technologies and services, the core ...

Caption The high-resolution images were collected on a Titan Krios cryo-electron microscope in collaboration with colleagues at Stanford University. The installation of the first Titan Krios ...

The correlative stage was developed out of the necessity for a tool that uses fluorescence microscopy to help localise structures of interest in samples for high-resolution cryo-electron microscopy ...