LIG4 syndrome is an exceptionally rare disorder caused by a genetic mutation that prevents the body from repairing damaged ...

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means ...

Our cells constantly receive DNA damage from factors such as ultraviolet rays, irradiations, toxins and chemicals. For women, ...

Cigarette smoke causes cancer primarily by damaging the DNA. A new study that mapped these damages has revealed that the way ...

In addition, there are a handful of syndromes with an etiological link to DNA damage and repair that exhibit symptoms of accelerated aging but have no striking neurological symptoms. Such ...

Cigarette smoke causes cancer primarily by damaging the DNA. A new study that mapped the DNA damages caused by smoking, ...

Our cells constantly receive DNA damage from factors such as ultraviolet rays, irradiations, toxins and chemicals.

The study, published in Nucleic Acids Research, focused on benzo (a)pyrene, a toxic chemical in cigarette smoke, which binds to DNA when processed by the body, and disrupts its normal function and ...

If these DNA breaks aren't repaired, they can prompt cells to self-destruct, or failing that, become cancerous.As LIG4 syndrome impairs this response, people with the condition are particularly ...

"Sunburn damages the DNA, leading to cell death and inflammation. So the textbooks say. But in this study we were surprised to learn that this is a result of damage to the RNA, not the DNA that ...