ATP-dependent RNA ligases join 3’-OH and 5’-PO 4 RNA termini via three nucleotidyl transfer steps similar to those of DNA ligases: (Step 1) ligase reacts with ATP to form a covalent ...

and sealing of the resultant recombined DNA molecules through the action of enzymes called ligases. Despite the complexity of this process, recombination events occur with remarkable accuracy and ...

After two fragments with complementary sticky ends are joined, the DNA backbone may be covalently sealed using another enzyme called DNA ligase.