In macrophages, DNAse II degrades DNA from engulfed apoptotic cells; results from a mouse study by Kawane et al. suggest that deficiency of this enzyme or failure to completely degrade engulfed ...

Patent for methods of use of topical DNase enzymes in the eye covers L304, Neutrolis' proprietary therapy in development for the treatment of moderate to severe dry eye disease CAMBRIDGE, Mass., Dec.

Under the agreement, Neutrolis has acquired the rights to intellectual property that covers the use of topical DNase enzymes in the eye. Neutrolis is developing L304, a novel DNase generated using ...