I suggest, therefore, that the initial diuretic regimen for patients with ascites who are not hospitalized should be based on doses of diuretics lower than those used by Angeli and colleagues (for ...

However, this standard approach often fails as CHF progresses and diuretic resistance occurs. In the management of diuretic resistance, appropriate attention should first be given to optimizing ...

Physiologic alterations in CHF, such as changes in absorption, distribution, metabolism, and elimination of drugs, can indeed alter loop diuretic pharmacokinetics; however, these effects do not ...