A quarter of the samples of Escherichia coli bacteria carried genes that made an enzyme called ESBL, which can destroy penicillin, cephalosporins and related antibiotics according to the report.

and it allowed for the faster consolidation of empiric antibiotics. This protocol also restricted ertapenem use to approval by an infectious diseases physician for documented ESBL infections.

on behalf of the ESBL: Attribution Consortium: Attributable sources of community-acquired carriage of Escherichia coli containing β-lactam antibiotic resistance genes: a population-based ...

Although additional testing is needed to prove the compound is safe and effective for use as a future antibiotic ... such as extended-spectrum beta-lactamase (ESBL) producing E. coli.