An article in the June issue (Nat. Biotechnol. 22, 773–774, 2004) highlights the challenge of producing a shared vocabulary that biologists can use to communicate their results effectively ...

Proteins have four levels of structure: primary (amino acid sequence), secondary (local folding patterns like alpha helices and beta sheets), tertiary (overall 3D shape), and quaternary (assembly of ...

Although the rational protein design approach offers an increased possibility of beneficial alterations, it is not easy to accurately predict the sequence-structure-function relationship, particularly ...