I was a young enzymologist looking for a new project, and immediately volunteered for this one, which involved a peptidase of apparently unique mechanism and an enzyme product of potentially great ...

These inhibitors are typically small molecules designed by considering the structure of the active site or the substrate specificity of the enzyme ... of the target protein is used as the template ...

In an organism, the active site of each enzyme is a different shape. It is a perfect match to the shape of the substrate molecule, or molecules. This is essential to the enzyme being able to work.

The peptide chains are formed from joining amino acids together in the form of a string, which is done by the ribosome. Two ...

Proteins are reduced to peptides prior to mass spectrometric analysis and protein digestion is a critical step in sample preparation and often a rate limiting step. Trypsin is the most commonly used ...

Click here to download Proteomics Unit Order Form as pdf. Protein / Peptide identification by LC-MS/MS Protein digestion in-gel or in-solution using a proteolytic enzyme, usually trypsin. Analysis is ...