The DNA sequence defines the outcome of this competition, which will change in response to the changing combinations of active transcription factors that are induced, for example, by cellular ...

For example, how many transcription factors ... Here, we present an analysis of 1,391 manually curated sequence-specific DNA-binding transcription factors, their functions, genomic organization ...

Mediator is a common target of DNA-binding transcription factors (TFs) and also interacts with various Pre-Initiation Complex (PIC) factors. The PIC consists of TFIIA, TFIIB, TFIID, TFIIE, TFIIF, ...

Abdenour Soufi from the University of Edinburgh reveals how transcription factors (TFs)—key proteins that regulate gene activity—navigate DNA and chromatin structures to determine cellular ...

for example, providing structure, organization and folding of DNA, but this paper is the first to demonstrate that a linker histone is also directly regulating gene expression as a transcription ...