A new clinical study shows that an inhibitor of Fas ligand (FasL), also called CD95 ligand (CD95L), led to a faster recovery of COVID-19 patients and reduced mortality. On average, it took eight ...

New in vivo evidence confirms that tumor-expressed Fas ligand impairs immune responses to cancer by inducing apoptosis of anti-tumor immune effector cells. A recent report demonstrated that murine ...

A recent study has uncovered key insights into the differing tumour rejection behaviours of chimeric antigen receptor T cells ...

This Fas ligand–induced caspase-independent death is absent in T cells that are deficient in either Fas-associated death domain (FADD) or receptor-interacting protein (RIP). RIP is also required ...

A new clinical study shows that an inhibitor of Fas ligand (FasL), also called CD95 ligand (CD95L), led to a faster recovery of COVID-19 patients and reduced mortality. On average, it took eight ...

the malignant cell can be lysed either through preformed granules or the Fas-Fas ligand pathway (Figure 1). A summary of the published data from these trials is summarized in Table 1. ANCAs ...