Thrombin mediates fibrin polymerization and is known to be involved in acute and chronic inflammatory processes in vivo. Flick et al. have used various genetically engineered mouse models to study ...

Tissue repair is another area of future application. “The fibrin matrix also facilitates tissue remodelling and regeneration by supporting cell migration and influencing cellular phenotype ...

If the leak continued, then fibrin glue was used as a tissue adhesive. Endoscopic application of the sealant was accomplished under direct vision via a double-lumen catheter passed through a ...

Platelets respond to the site of injury and become activated, releasing substances such as growth factor, adenosine diphosphate, prostaglandins, and fibrin-stabilizing factor. They change their ...