We used a novel geometric hyperbranched RCA (HRCA) reaction to detect point mutations in small amounts ... 39-base sequence adjacent to the G542X locus of the CFTR gene. The probe contained ...

and G542X rats, in addition to maintenance of wild-type Sprague Dawley strain for additional use Generation and procurement of novel relevant CF animal models to understand newly developed CFTR ...

The Cftr-G542X knock-in mouse line (Cftr G542X): Useful to examine nonsense suppression therapies that target either nonsense suppression or nonsense mediated decay (NMD) inhibition because the G542X ...