In particular, the work reveals that modulating glutamine metabolism is a potential therapeutic route for common red blood cell disorders. Additionally, glutamine abundance may serve as a tool for ...

A research group led by Kazunobu Sawamoto, a professor at Nagoya City University and National Institute for Physiological Sciences, and Koya Kawase, a pediatric doctor at Nagoya City University ...

They noticed that breast cancer cells adapt to glutamine starvation by switching on a pathway that generates a critical metabolite called alpha-ketoglutarate, normally derived from glutamine.