Nowhere has this been more true than in the grading of astrocytomas ... while children and adults do poorly. Low-grade gliomas in adults tend to transform into high-grade glioma while in ...

Low-grade gliomas in adults tend to transform into high-grade glioma while in pediatrics they rarely do so. Mutations can differ by age; IDH1 mutations common in adult low-grade glioma are rare in ...