Researchers discovered that a chemical alteration on a single protein, histone H3, is essential for controlling the genes that help cells remember their own identity and function. When the genes ...

Researchers unveil histone-based age predictors, offering a new window into epigenetic aging and its shared patterns across ...

Each histone octamer is composed of two copies each of the histone proteins H2A, H2B, H3, and H4. The chain of nucleosomes is then wrapped into a 30 nm spiral called a solenoid, where additional ...

In eukaryotes, DNA is tightly wound into a complex called chromatin. Thanks to the process of chromatin remodeling, this complex can be "opened" so that specific genes are expressed. Various ...

One of those genes was similar to a gene known to create a linker histone protein in Arabidopsis, a plant in the mustard family that is widely used in plant biology research. By using an ...

LMU molecular biologist Gunnar Schotta decodes the epigenetic silencing of problematic retroviral gene sequences.

One of those genes was similar to a gene known to create a linker histone protein in Arabidopsis, a plant in the mustard family that is widely used in plant biology research. By using an Arabidopsis ...

Modifying histones can affect transcription by altering the structure of chromatin and by facilitating interactions with accessory proteins that recognize modified histones. Thus, histone ...

A recent study delves into the pivotal role of Setd2, a histone methyltransferase enzyme, in embryonic development within ...