Researchers from the University College Cork have described the neuroprotective effect of TMP-269, a class-IIa-specific histone deacetylase (HDAC) inhibitor in preclinical models of PD. Pan-inhibitors ...

Romidepsin and vorinostat have very different chemical structures and, whereas vorinostat is a pan-HDAC inhibitor, romidepsin is thought to be more selective for class I HDACs. However ...