Some antigens only occur in certain ethnic ... In essence, the anti-HLA antibodies can bind to regions of bead-coupled HLA molecules that are normally not accessible if they are masked by ß2 ...

The TRACeR I platform was incorporated into a humanized antibody fragment in a bispecific T-cell engager (BiTE) format. When ...

Additionally, detection of both anti-MHC class I and class II antibodies was problematic. The predominant problem underlying class distinction arises from the distribution of HLA antigens.

Findings published in Science Immunology resolve how human LAG-3 binds to its main ligand providing a better foundation for ...

Clinical-stage company Immutep (ASX:IMM) has announced new findings published in Science Immunology that resolve how human ...

Novel vaccine platform improved protection against diverse influenza subtypes when tested in animal models and human ...

Cancer immunotherapy has revolutionised treatment for patients, whereby the body’s own immune system is harnessed to destroy ...

This image shows the structure of an antibody (Y-shaped) and how it binds to different types of antigens (color-coded shapes at the top). The antibody's binding sites, located at the ends of its arms, ...

Led by Professor Jamie Rossjohn at Monash University's Biomedicine Discovery Institute (BDI), in Melbourne, Australia, in ...

The structure of an antibody can be divided into several key regions: Variable Regions (Fab): Located at the tips of the Y-shaped molecule, the variable regions contain the antigen-binding sites.