Although patients with Loeys-Dietz syndrome are at risk of developing aneurysms in all arteries, the base of the aorta closest to the heart is the site at greatest risk, the researchers say.

In 2006, a team led by Harry "Hal" Dietz, M.D., discovered that treating Marfan mice with losartan (Cozaar) dramatically strengthens the aorta, the major artery carrying blood away from the heart ...