MSI analysis has been a useful tool for HNPCC screening and for determining prognosis in HNPCC and sporadic cases of CRC (ref. 2). Three recent papers add support for the use of MMR genetic ...

Lynch syndrome, also called hereditary non-polyposis colorectal cancer (HNPCC), is one of the leading causes of hereditary cancers (e.g., colorectal and endometrial cancer), which can be prevented or ...

a HNPCC-associated cancers include endometrial ... the cancers and in the development biomarkers for early detection of disease. Competing Interests: The authors declared no competing interests.

Lynch syndrome (LS) is a condition that can run in families. It is also known as hereditary non-polyposis colorectal cancer (HNPCC). It is caused by an alteration in a gene called a mismatch ...

MSI and dMMR are hallmarks of colorectal cancer (CRC) and can identify cases of Lynch syndrome, also known as hereditary nonpolyposis colorectal cancer (HNPCC). Testing for these markers has ...