However, we recently found that the CMY-10 ESBL had higher imipenem-hydrolysing activity than OXA-23, a class D carbapenemase 7,10. Gram-negative ... Figure 1: A sequence alignment of amino ...

Background: Infections caused by extended-spectrum β-lactamase (ESBL)–producing gram-negative organisms ... those achieved with group 2 carbapenems (imipenem, meropenem, doripenem).