We need a holistic approach to better integrate our knowledge of innate immune pathways. Fundamentally, we aim to understand the regulatory mechanisms of cGAS-STING. We’ve identified a few ...

Researchers have discovered a protein variant that serves as a knob for regulating the body's innate immune response. The findings could lead to new therapies for Long COVID, autoimmune disorders, and ...

"Living organisms have evolved complex pathways to sense, signal, and repair damaged DNA," he says. "Here we're learning new ...

There is significant crosstalk between DNA damage response (DDR) pathways and innate immune pathways. Both the individual pathways and their interactions are key areas of interest for the ...

Given the high conservation of Cullin family proteins and innate immune signaling pathways in Drosophila and mammals, the ...

A study by Tulane University researchers has uncovered new insights into how biological sex differences can influence tumor ...

Vitamin D modulates T-cell responses and has anti-inflammatory properties, but boosts innate immune responses by induction ... the vitamin D–cathelicidin pathway. Supplementation of humans ...

The innate immune response is the body's first line ... and how the newly identified 2'3'-cGAMP/Rab18/FosB signaling pathway ...

Vitamin D modulates T-cell responses and has anti-inflammatory properties, but boosts innate immune responses by induction ... the vitamin D–cathelicidin pathway. Supplementation of humans ...