One of the first antibodies we supported was against LRRK2, a protein kinase associated with the initiation and progression of Parkinson’s. In 2018, we coordinated development of an antibody ...

Future Neurology. 2012;7(2):145-153. Taken together, the present studies do not support a direct biochemical interaction between α-syn and LRRK2, or direct phosphorylation of α-syn by LRRK2 ...

The team's work sheds light on the pivotal role of Lrrk2, a major risk gene for Parkinson's disease, in modulating macrophage functions and immune responses. Parkinson's disease (PD) is a ...